How NUT's Polyunsaturated Fat Reference Values Are Derived

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How NUT's Polyunsaturated Fat Reference Values Are Derived

The essential polyunsaturated fats are substances our bodies cannot make and participate in so many important bodily functions that they deserve a place on a nutrition program's main screen alongside the essential vitamins and minerals.

Tissue HUFA Maintenance, Lands (1992) NUT incorporates an empirical equation from Dr. William Lands that relates polyunsaturated fatty acid consumption to resulting percentages of Omega-6 highly unsaturated fatty acids in plasma phospholipids over the long term. The NUT reference values are refigured every time you do a reset from the analysis screen and they take into consideration all the fatty acids in the diet. NUT's modus operandi is to accept the user's levels of dietary Omega-6 fatty acids as 100% and find a balancing level of Omega-3 as directed by Lands' equation. When this feature is turned on, you can raise the EPA and DHA percentages in the analysis either by increasing Omega-3 or reducing Omega-6 in your diet. If you would like to change NUT's target for the "Omega-6/3 Balance" value, you can do so in "Set Personal Options", "Essential Fatty Acid Options." The maximum amount of EPA+DHA allowed can also be changed. If the allowed EPA+DHA amount is below the amount necessary to reach the target, NUT will then show by how much Omega-6 must be lowered. If you would like to set your own reference values to exactly how you are eating, do an "e" reset on a characteristic period and then go to "Set Personal Options", "Essential Fatty Acid Options". Take "Accept current reference values as absolute amounts", and then when you come back to the analysis screen, reset with "m", "n", or "o". The program comes with Lands' equation turned OFF by default, and in this case, the maximum amount of EPA+DHA allowed becomes the amount that satisfies 100% of EPA+DHA in the analysis.

Tissue HUFA Diversity The scatterplot at the right shows actual levels of highly unsaturated fatty acids in plasma phospholipids for a population sample, with the first number of the "Omega-6/3 Balance" value indexed on the bottom axis. The median values for each type of HUFA shown in the graph as well as the balance point for EPA and DGLA are all near an "Omega-6/3 Balance" value of 55/45, which is the target that Lands' group recommends. Another goal you will see cited by other groups is a ratio of AA to EPA of 1.5, which according to the graph appears to be very near an "Omega-6/3 Balance" value of 40/60.

NUT comes preset with Lands' equation turned off because I personally got so many side-effects from higher levels of Omega-3 fatty acid supplementation and usually felt markedly worse mostly because Omega-3 can raise fasting blood sugar and cause anxiety. For me, the most obvious and unambiguous deficiency symptom for EPA+DHA is a fatalistic depression; for ALA, a mild bronchitis, a less joyful mood, and unruly hair. I have tried to figure my requirement for these nutrients several times under wildly different dietary strategies that included large differences in the amounts of Omega-6. Each time I have clearly seen the maximum amount I could regularly eat without side-effects to average 0.6 grams per day of EPA+DHA and 1.2% of calories from ALA.

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